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Background Malaria remains the top infectious disease threat facing the U.S. military in many forward operating environments. Compliance with malaria chemoprophylaxis remains a critical component in preventing malaria in the deployed Service Member. Studies of previous military operations show that compliance is consistently higher with weekly versus daily dosing regimens. Current FDA approved weekly chemoprophylaxis options have contraindications that can limit prescribing. The combination of chloroquine (CQ) with azithromycin (AZ) has previously been shown to be an efficacious treatment option for malaria, has pharmacokinetics compatible with weekly dosing, and has shown synergy when combined in vitro. Methods In this open label study, 18 healthy volunteers, aged 18–50 years (inclusive), were randomly assigned to receive either 300 mg CQ or 300 mg CQ and 2 gm azithromycin (CQAZ) of directly observed therapy, weekly for 3 weeks prior to undergoing mosquito bite challenge with chlor...
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2018 •
Зроблено аналіз споживання електроенергії системами зовнішнього освітлення в окремих регіонах України за 2016 рік. Проведено техніко-економічний розрахунок вартості автономної енергетичної системи.The analysis of electricity consumption by the systems of outdoor lighting in some regions of Ukrainefor 2016 year. The technical and economic calculation of the cost of the autonomous power system have been carried out
Psihološka obzorja / Horizons of Psychology
Psihosocialne značilnosti učencev kot napovedniki različnih oblik medvrstniške viktimizacije in nasilnega vedenja2007 •
2007 •
Journal of Nepal Medical Association
Cysticerci in Palpable Nodules Diagnosed on Fine Needle Aspiration Cytology2009 •
Fundamenta Informaticae
Towards a formal femantics for the process model of the taverna workbench. Part i2009 •
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2018 •
Inorganica Chimica Acta
A ‘donor-free’ chromophore with a silicon-based acceptor group for second order nonlinear optics2022 •
Imprensa da Universidade de Coimbra eBooks
Quando as fontes nos falam sobre os documentos: dois estudos de caso relacionados à ciência coimbrã2016 •
Kleronomia. Α Scientific Journal Published Twice - Yearly
A. Siskos, "Challenges and Ontological Basis of the Ecumenical Movement. An Orthodox View", Kleronomia 39 (2016-2017) [2021], pp. 237-248.2021 •
Journal of Biomechanics
The influence of cryopreservation and quick-freezing on the mechanical properties of tendons2017 •
International Journal of Research in Engineering and Technology
Wavelet Based Ecg Signal Component Identification2014 •
arXiv: General Relativity and Quantum Cosmology
Cosmological scenarios in quantum cosmology of Brans-Dicke theory of gravity on Einstein and Jordan frames2017 •